There were only a couple of things that really bothered me with the first Mass Effect. One was the large amount of pop-in. When the game had all its textures, it looked really nice, but it was really annoying when it took about four seconds for the level of detail to catch up to the camera.
I didn't mind the Mako missions that much. It might just be a throwback to how I played Morrowind, which was to just wander aimlessly until I got so bored I returned to the story, or stumbled into it by accident. After my first play through, I would visit all the "uncharted worlds" I could first, just for the xp, before heading back to those three story content worlds. I did not like the invisible walls on the "Liara's dig site" planet. By that time, I'd climbed several extra terrestrial versions of everest, so being unable to navigate up a small hill smacked of a lack of foresight in game design.
Since it's Bioware, the story will be, at the very least, passable, so that aside - With tightened AI, squad control, textures that aren't perpetually running late, and with some more variety in landscapes (including some that feel truly foreign and alien instead of simply being homogenized copies with different colored skies...) I'd be pretty happy.
Vagrancy - Be careful who you wake up in a twenty four hour parking lot.
His name was Not Johnny - A young man becomes a sort of superhero after a crippling injury. He