That is indeed a very important question.
I often wonder myself, why anime characters have such large eyes. I personally believe it is the asians way of compensating for their lack of wide-eyes. I mean... it's nice to dream, right? If say, I had very small hands, I would probably draw pictures of people with large hands. Or, like Medieve, all of my characters would have very large penises.
This is just my theory, though.
I'm talking more about people on this forum, who use the same art style in their games, without exploring other styles of anime, or art, period.
And it's no secret that the japanese do indeed like to incorperate things to "compensate" in their toons. In dbgt, the jap version, goku loses his clothes frequently(as a joke, not for perverted reasons, different culture, different humor)his penis is 2 feet long. In a lot of anime, the breasts are ALWAYS double D's, and even in old paintings and art from the meji eras, they had pictures of women with large breasts, because it was seen as a sign of beauty, that and they don't (usually) have large breasts, so, yea.
But my point is EVERYONE is using that style in rpgs now, not just the japs. In fact, I'm not at all referring to the japs, who often DO actually explore more realistic styles of anime, in action anime, or in ones more directed at adults. I don't see hardly any FAN GAMES that don't use the simplified, cartoony manga look.
For example, you can find lots of great anime that look like this:
http://myweb.tiscali.co.uk/scribblemoose/images/wolfsrain/wrkiba1.jpgor even more realistic like this:
http://img114.imageshack.us/img114/3409/bea2vn7.jpgNotice they're more "eye-shaped as apposed to the aforementioned, and you can get even more realistic... i have yet to find many fan games that try to be more realistic with their look and style...