Amatsuki
Code Geass - 2nd Season
The Melancholy of Haruhi Suzumiya - 2nd Season
Rosario + Vampire
Mushi-Uta - 2nd Season (Is there a second season?)
Persona -trinity soul-
Mirai Nikki
Kite Liberator
That's my list for upcoming anime (they're all listed on the site, but some are Spring 2008). Rosario + Vampire is definitely not my cup of tea, but the poster looks so darned cool I'll just have to watch the first episode to see if the animation is any good. Kite Liberator sounds interesting, and it's by the same people who did Mezzo Forte, so it should be cool (as long as they avoid the gratuitous sex scenes). Mirai Nikki is the crazy stuff I've read in recent memory (creepy stalker girl taking people apart with an axe), so of course I have to watch that, provided the animation doesn't suck and they don't screw up the plot.
I'm also looking forward to Persona and Amatsuki, the latter because I've read the manga and I'd like to see how they animate it, and the former because... well, it's Persona, man.
Other than that, most of them look like series I wouldn't be quite interested in. But hey, only time can tell: I was skeptical about Gurren Lagann when it first came out, and it took me until episode 11 aired to finally watch the first episode and find out how awesome it was.